- Original Article
- Neonatology (Perinatology)
- Individualized ibuprofen treatment using serial B-type natriuretic peptide measurement for symptomatic patent ductus arteriosus in very preterm infants
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Jeonghee Shin, Eun Hee Lee, Jee Hyun Lee, Byung Min Choi, Young Sook Hong
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Clin Exp Pediatr. 2017;60(6):175-180. Published online June 22, 2017
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Purpose Plasma level of B-type natriuretic peptide (BNP), an emerging, sensitive, and specific biomarker of hemodynamically significant patent ductus arteriosus (PDA), rapidly decreases in infants receiving cyclooxygenase inhibitors for ductal closure. We investigated the usefulness of serial BNP measurement as a guide for individual identification of early constrictive responses to ibuprofen in preterm infants with symptomatic PDA (sPDA). MethodsBefore March 2010, the... |
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- The influencing factors on procalcitonin values in newborns with noninfectious conditions during the first week of life
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Jueseong Lee, Yong Hyeon Bang, Eun Hee Lee, Byung Min Choi, Young Sook Hong
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Clin Exp Pediatr. 2017;60(1):10-16. Published online January 16, 2017
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Purpose Although procalcitonin (PCT) level is useful for the diagnosis of neonatal sepsis, PCT reliability is inconsistent because of the varied conditions encountered in neonatal intensive care units. This study aimed to investigate PCT levels and factors influencing increased PCT levelin newborns without bacterial infection during the first week of life. MethodsIn newborns hospitalized between March 2013 and October 2015, PCT levels... |
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- Nephrology (Genitourinary)
- Impaired angiogenesis in the enalapril-treated neonatal rat kidney
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Hyung Eun Yim, Kee Hwan Yoo, Eun Soo Bae, Young Sook Hong, Joo Won Lee
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Clin Exp Pediatr. 2016;59(1):8-15. Published online January 22, 2016
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Purpose Nephrogenesis is normally accompanied by a tightly regulated and efficient vascularization. We investigated the effect of angiotensin II inhibition on angiogenesis in the developing rat kidney. MethodsNewborn rat pups were treated with enalapril (30 mg/kg/day) or vehicle (control) for 7 days after birth. Renal histological changes were checked using Hematoxylin & Eosin staining. We also investigated the intrarenal expression of vascular... |
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- Effect of angiotensin II inhibition on the epithelial to
mesenchymal transition in developing rat kidney
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Hyung Eun Yim, Kee Hwan Yoo, In Sun Bae, Young Sook Hong, Joo Won Lee
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Clin Exp Pediatr. 2009;52(8):944-952. Published online August 15, 2009
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Purpose:To investigate the effects of angiotensin II inhibition on the epithelial to mesenchymal transition (EMT) in the developing
kidney, we tested the expression of EMT markers and nestin in angiotensin converting enzyme (ACE) inhibitor-treated
kidneys.
Methods:Newborn rat pups were treated with enalapril (30 mg/kg/d) or a vehicle for 7 days. Immunohistochemistry for the
expression of α-smooth muscle actin (SMA), E-cadherin, vimentin, and nestin were... |
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- Functional recovery after transplantation of mouse bone marrow-derived
mesenchymal stem cells for hypoxic-ischemic brain injury in immature rats
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Wooksun Choi, Hye Kyung Shin, So-Hee Eun, Hoon Chul Kang, Sung Won Park, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee, Baik-Lin Eun
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Clin Exp Pediatr. 2009;52(7):824-831. Published online July 15, 2009
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Purpose : We aimed to investigate the efficacy of and functional recovery after intracerebral transplantation of different doses of mouse mesenchymal stem cells (mMSCs) in immature rat brain with hypoxic-ischemic encephalopathy (HIE).
Methods : Postnatal 7-days-old Sprague-Dawley rats, which had undergone unilateral HI operation, were given stereotaxic intracerebral injections of either vehicle or mMSCs and then tested for locomotory activity in... |
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- Case Report
- Two cases of Smith-Magenis syndrome
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Seong Kwan Jung, Kyu Hee Park, Hae Kyung Shin, So Hee Eun, Baik-Lin Eun, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee, Sook Young Bae
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Clin Exp Pediatr. 2009;52(6):701-704. Published online June 15, 2009
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SmithMagenis syndrome (SMS) is a rare disorder with multiple congenital anomalies caused by a heterozygous interstitial deletion involving chromosome 17p11.2, where the retinoic acid-induced 1 (RAI1) gene is located, or by a mutation of RAI1. Approximately 90% of the patients with SMS have a detectable 17p11.2 microdeletion on fluorescence in-situ hybridization (FISH). SMS is characterized by mental retardation, distinctive behavioral... |
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- Original Article
- Evaluating and managing hypertension in children: a survey of Korean cardiologists and nephrologists
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Eun Hee Lee, Hyung Eun Yim, Gi Young Jang, Kee Hwan Yoo, Chang Sung Son, Young Sook Hong, Joo Won Lee
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Clin Exp Pediatr. 2008;51(9):992-997. Published online September 15, 2008
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Purpose : Hypertension (HTN) is no longer an exclusively adult disease; the prevalence of pediatric HTN is increasing. To understand the evaluation and treatment of childhood HTN in Korea, we investigated, via a questionnaire, how hypertensive children are currently assessed and managed by pediatric cardiologists (CA) and nephrologists (NE).
Methods : We surveyed 82 pediatric CA and 77 NE, regarding... |
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- Use of herbal medicine in epileptic children
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Jee Yeon Lee, Wook Sun Choi, So-Hee Eun, Baik-Lin Eun, Young Sook Hong, Joo Won Lee
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Clin Exp Pediatr. 2008;51(4):415-419. Published online April 15, 2008
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Purpose : Herbal medicine is thought to be widely used by children with epilepsy, but there have been few studies. This study aimed to investigate the perceptions and the actual conditions of usage of herbal medicine by children with epilepsy.
Methods : From July to August 2007, three hundred seventy eight questionnaires were completed by parents of epileptic children who visited... |
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- Efficacy and safety of oxcarbazepine in epileptic children
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Hye Kyung Shin, Yoon Lee, Jee-Yeon Lee, Wooksun Choi, So-Hee Eun, Baik-Lin Eun, Young Sook Hong, Joo Won Lee
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Clin Exp Pediatr. 2008;51(2):162-169. Published online February 15, 2008
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Purpose : Oxcabarzepine (OXC), newly recommended antiepileptic drug, has been prescribed for patients with partial seizures and generalized tonic clonic seizures in Korea from 1999. There are limited reports about an efficacy of OXC therapy in epileptic children in Korea. This study evaluated the efficacy and safety of OXC in the light of our experience.
Methods : The patients, who had... |
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- Case Report
- Perforation of azygos vein and right-sided hydrothorax caused by peripherally inserted central catheter in extremely low birth weight infant
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Kee Soo Ha, Jung Yeon Shin, Mi Jung Hwang, Young Ok Choi, Dong Han Shin, Gi Young Jang, Byung Min Choi, Kee Hwan Yoo, Young Sook Hong, Chang Sung Son
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Clin Exp Pediatr. 2006;49(8):902-905. Published online August 15, 2006
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We report a case in which routine chest roentgenograms of an 840 g infant led to the belief that the peripherally inserted central catheter (PICC) was appropriately positioned within the superior vena cava when, in actuality, it was within the azygous arch. Although many cases of pleural effusions have been reported to be caused by a central venous catheter, a... |
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- Primary peritoneal drainage as a treatment for perforated necrotizing enterocolitis with bacterial peritonitis in an extremely low birth weight infant : a case report
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Wook Sun Choi, Il Hong Moon, Jang Hoon Lee, Seung Hwa Lee, Byung Min Choi, Baik-Lin Eun, Young Sook Hong, Joo Won Lee
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Clin Exp Pediatr. 2006;49(7):800-804. Published online July 15, 2006
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Necrotizing enterocolitis(NEC) is the most common life-threatening surgical emergency in neonates, and remains a major cause of morbidity and mortality. In addition to conventional laparotomy, intraperitoneal drains have been used for the treatment of perforated NEC, especially in extremely low birth weight(ELBW) infants. We report a case of perforated NEC with bacterial peritonitis in an ELBW infant managed with primary... |
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- Original Article
- The auditory evoked potential in premature small for gestational age infants
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Il Hong Moon, Kee Soo Ha, Gui Sang Kim, Byung Min Choi, Baik-Lin Eun, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee
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Clin Exp Pediatr. 2006;49(12):1308-1314. Published online December 15, 2006
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Purpose : This study aimed to evaluate the usefulness of auditory evoked potential (AEP) in clarifying neuronal development in premature small for gestational age (SGA), and appropriate for gestational age (AGA) infants.
Methods : A total of 183 premature infants who were born from August 2002 to July 2005, were examined with AEP. They were divided into three groups; AGA, symmetric-SGA... |
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- The effects of ibuprofen and indomethacin therapy for patent ductus arteriosus in preterm infants
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Wooksun Choi, Jung-Yeon Shin, Byung Min Choi, Baik-Lin Eun, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee
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Clin Exp Pediatr. 2006;49(12):1315-1323. Published online December 15, 2006
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Purpose : This study was conducted to compare the efficacy and safety of ibuprofen and indomethacin in the treatment of patent ductus arteriosus (PDA) in preterm infants and to determine whether ibuprofen can be an alternative drug.
Methods : A total of 32 preterm infants with symptomatic PDA were enrolled in the study. Twelve infants received intravenous ibuprofen 10 mg/kg, followed... |
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- Usefulness of modified ambu in patients who need artificial ventilation
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Kee Soo Ha, Il Hong Moon, Hee Sun Lee, Dong Han Shin, So Hee Eun, Baik-Lin Eun, Young Sook Hong, Joo Won Lee
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Clin Exp Pediatr. 2006;49(11):1194-1201. Published online November 15, 2006
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Purpose : The comatose mentality can be catastrophic, especially if the condition is severe or the duration is prolonged. Therefore, delayed diagnosis can result in a poor outcome or death. The best radiologic modality to differentiate from cerebral lesions in patients suffering from cerebral diseases is magnetic resonance imaging (MRI) rather than computed tomography (CT). Special apparatuses with metal... |
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- Usefulness of Korean Infant Developmental Screening Test in Premature Infants
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Dong Han Shin, Hee Sun Lee, Jee Yeon Lee, Byung Min Choi, Baik-Lin Eun, Young Sook Hong, Joo Won Lee
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Clin Exp Pediatr. 2005;48(12):1337-1341. Published online December 15, 2005
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Purpose : This study aimed to evaluate the usefulness of Korean Infant Development Screening Test in predicting delayed development in premature infants.
Methods : A total of 74 children with histories of prematurity, who visited the pediatric neurology clinic of Korean University Ansan Hospital from August, 2002 to July, 2004, were examined, using the Korean Infant Development Screening Test. They were... |
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- Case Report
- A Case of Partial Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency Presenting as Uric Acid Lithiasis
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Ji Hae Kim, Mi Jung Kim, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee, Soon Kyum Kim
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Clin Exp Pediatr. 2004;47(9):1020-1023. Published online September 15, 2004
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The deficiency of enzyme hypoxanthine-guanine phosphoribosyltransferase(HPRT) results in hyperuricemia and subsequently manifests in diverse symptoms. Lesch-Nyhan syndrome is a disorder characterized by hyperuricemia, mental retardation, choreoathetosis, spasticity and self-mutilation, resulting from complete deficiency of the enzyme, whereas partial deficiency of the enzyme shows symptoms of milder forms more often without abnormal neurologic signs. A 7-year-old boy with normal growth and... |
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- Original Article
- A Multivariate Analysis of Risk Factors of Renal Involvement in Henoch-Sch nlein Purpura
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Min Jee Jeoung, Hyung Eun Yim, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee, Soon Kyum Kim
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Clin Exp Pediatr. 2004;47(4):405-411. Published online April 15, 2004
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Purpose : Long-term prognosis of Henoch-Sch nlein purpura(HSP) is determined by the existence and severity of renal involvement. We evaluated the relationship between various clinical features of HSP and the development of renal involvement using univariate and multivariate analyses for early detection and proper management of HSP nephritis.
Methods : We performed a retrospective study of 200 children who were diagnosed... |
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- Risk Factors for the First-Year Relapse in
Children with Nephrotic Syndrome
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Hye Kyoung Shin, Ji Hee Kim, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee, Soon Kyum Kim
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Clin Exp Pediatr. 2003;46(9):889-892. Published online September 15, 2003
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Purpose : This study aimed to evaluate risk factors of the first year relapse in children with nephrotic syndrome(NS) without the need for biopsy.
Methods : We reviewed, retrospectively, 78 children diagnosed with steroid responsive nephrotic syndrome between July 1997 and June 2002. Median years to follow up were 4.4 years(range : 1-5 years). We divided the patients into two groups(group... |
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- Case Report
- A Case of Intestinal Lymphangiectasia
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Hyung Eun Yim, Min Ji Jung, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee, Soon Kyum Kim
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Clin Exp Pediatr. 2003;46(9):921-925. Published online September 15, 2003
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Intestinal lymphangiectasia, one of the protein-losing gastroenteropathies, is an uncommon disease characterized by dilated intestinal lymphatics, enteric protein loss, edema, hypoalbuminemia, and lympocytopenia. Small bowel biopsy and CT have been used to confirm the diagnosis of intestinal lymphangiectasia. Small bowel biopsy shows collections of abnormal dilated lacteals in submucosa with distortion of villi and CT findings have been described as... |
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- Original Article
- Effects of Endothelin A Receptor Antagonist to Cellular Proliferation and Apoptosis in Neonatal Rat Heart
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Byung Min Choi, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee, Soon Kyum Kim
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Clin Exp Pediatr. 2003;46(7):668-678. Published online July 15, 2003
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Purpose : In order to investigate the role of endothelins in the cardiac development, the present study was designed to examine the effects of endothelin A receptor(ETAR) antagonist to the cellular proliferation and apoptosis in the neonatal rat heart. In addition, the expression of various regulatory genes in protein and mRNA levels by ETAR antagonist were examined.
Methods : Neonatal... |
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- Recurrence and Follow-up after Urinary Tract Infection
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Ji Hee Kim, Hye Kyung Shin, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee, Soon Kyum Kim
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Clin Exp Pediatr. 2003;46(6):561-565. Published online June 15, 2003
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Purpose : Urinary tract infection(UTI) is the most common bacterial infectious disease that may induce severe renal injury unless early diagnosis and appropriate treatment are performed. If recurrent UTI is prevented, renal injury can be also reduced. Therefore, we studied the risk factors of recurrent UTI in children.
Methods : We performed a retrospective study of 168 children(58 girls and 110... |
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- Case Report
- A Case of Graves Disease with Kyphosis by Osteoporosis
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Yo Won Na, Kee Hyoung Lee, Kee Hwan Yoo, Young Sook Hong, Ju Won Lee, Soon Kyum Kim
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Clin Exp Pediatr. 2001;44(8):971-975. Published online August 15, 2001
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Graves disease is the most common clinical feature of hyperthyroidism in childhood. Clinical manifestations include emotional lability, hyperactivity, tremor, excessive sweating, exophthalmos and weight loss. In Graves disease, osteoporosis could occur because of a disturbance of mineral homeostasis which rarely develops from reduced calcium absorption of the gastrointestinal tract and increased urinary calcium excretion related to an increased bone resorption.... |
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- Original Article
- The Role of Aldosterone on the Development of Renal
Tubular Reabsorption in Low Birth Weight Infants
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Byung Min Choi, Hoe Kyoung Koo, Jin Won Yook, Kyoung Bum Kim, Gi Young Jang, Moon Hee Kim, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee, Soon Kyum Kim
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Clin Exp Pediatr. 2001;44(11):1233-1242. Published online November 15, 2001
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Purpose : To determine the postnatal changes in aldosterone action on the renal tubular reabsorption in low birth weight(LBW) infants, we assessed the relation of the aldosterone concentrations to renal parameters during the first 10 days of life.
Methods : Twenty LBW infants were evaluated and their gestational ages ranged from 32.4 to 39.3 weeks and their birth weights ranged from... |
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- Evoked Potentials and Cranial Ultrasonography as a
Prognostic Method in Newborn with Asphyxia
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Hyung Jin Kim, Hee Kang, Byoung Min Choi, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee, Soon Kyum Kim
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Clin Exp Pediatr. 2001;44(10):1162-1167. Published online October 15, 2001
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Purpose : This study was aimed at finding a diagnostic tool which is useful in predicting the neurologic outcome of the asphyxiated newborns.
Methods : 31 newborns with asphyxia were evaluated by brainstem evoked potentials and cranial ultrasonography(CUS). During the neonatal follow-up, we evaluated the development of the babies with Bayley Scale of Infant Development II and INFANIB on corrected age... |
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- Assessment of Endogenous Nitric Oxide Formation in the Neonate : Measurement of Urinary Nitrite and Citrulline Concentrations
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Young Ho Kim, Ki Hwan Yu, Young Sook Hong, Sun Kyum Kim
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Clin Exp Pediatr. 2001;44(1):40-45. Published online January 15, 2001
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Purpose : At birth, as the fetus adjusts to the “new world”, the fetal pulmonary circulation undergoes a striking transition, characterized by an immediate rise in pulmonary blood flow and a sustained decrease in pulmonary vascular resistance(PVR). In the factors which reduce PVR after birth, are ventilation of the lung by gas, increase of oxygen tension in pulmonary vascular system,... |
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- Usefulness of Plasma Atrial Natriuretic Peptide Concentration in the Diagnosis of Patent Ductus Arteriosus in Preterm Infants
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Byung Min Choi, Jae Kyun Yoon, Hyun Hee Lee, Hae Won Cheon, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee, Soon Kyum Kim
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Clin Exp Pediatr. 2000;43(7):897-904. Published online July 15, 2000
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Purpose : Diagnosis of a hemodynamically significant patent ductus arteriosus(PDA) that should
be treated is difficult to determine by clinical and echocardiographic examinations. The aim of this
study was to clarify the interrelationship of plasma atrial natriuretic peptide(ANP) concentrations
and clinical signs or echocardiographic signs of PDA in preterm infants and use plasma ANP
concentrations as a diagnostic indicator of a hemodynamically significant PDA.
Methods... |
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- Case Report
- A Case of Factor Ⅶ Deficiency Presenting as Hemarthroses
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Han Seong Ko, Kee Hwan Yoo, Kwang Chul Lee, Young Sook Hong, Joo Won Lee, Soon Kyum Kim
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Clin Exp Pediatr. 2000;43(3):428-431. Published online March 15, 2000
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Factor Ⅶ deficiency has an estimated incidence of 1/500,000 in the general population and autosomal recessive pattern of inheritance. Factor Ⅶ deficiency is characterized by prolonged prothrombin time(PT), and normal activated partial thromboplastin time(aPTT) and bleeding time(BT). Definite diagnosis of this condition requires a specific Factor Ⅶ assay. The clinical features are variable and do not always correlate with the... |
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- A Case of 18q-Deletion Syndrome with Hydronephrosis and Anhydrosis
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Mun Hee Kim, Kee Hwan Yoo, Young Sook Hong, Soon Kyum Kim
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Clin Exp Pediatr. 1999;45(5):711-715. Published online May 15, 1999
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The 18q-syndrome is a deletion disorder that occurs in humans. Clinical symptoms are mental retardation, craniofacial anomalies, skeletal deformity, seizure, and hearing loss. 18q- deletion occurs over a broad region, spanning the interval from 18q22.2 to 18qter rather than a single critical region containing 18q. We experienced a case of 18q-syndrome in a male child. It was diagnosed by clinical... |
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- Original Article
- Effects of Angiotensin Converting Enzyme Inhibition into Apoptosis and Related Genes in the Neonatal Rat Kidney
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Kee Hwan Yoo, Haewon Cheon, Byung Min Choi, Young Sook Hong, Joo Won Lee, Soon Kyum Kim
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Clin Exp Pediatr. 1999;42(8):1086-1095. Published online August 15, 1999
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Purpose : The renin-angiotensin system plays an important role in renal growth and development. Exposuring the neonate to angiotensin converting enzyme(ACE) inhibitor increases mortality and results in growth retardation and abnormal renal development. ACE inhibition in the developing kidney reduces the renal expression of TGF-β1 and EGF, which may account for renal growth impairment. This study was designed to... |
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- Prognostic Factors for Mortality in Neonates with Respiratory Distress Syndrome After Surfactant Replacement Therapy
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Nam Soo Kang, Byung Min Choi, Young Sook Hong, Joo Won Lee, Soon Kyum Kim
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Clin Exp Pediatr. 1998;41(9):1188-1197. Published online September 15, 1998
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Purpose : To evaluate the association between neonatal mortality and the initial response to surfactant replacement therapy, and to examine the correlation between the response type and other prognostic factors.
Methods : Sixty-seven neonates with respiratory distress syndrome(RDS) were divided into two groups; group I(n=51) who survived and group II(n=16) who died within the first 28 days of life after one... |
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- Study of a Comparison of Ultrasonography with Radiography to Localize the Umbilical Arterial Catheter
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Byoung Min Choi, Young Kwan Park, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee, Soon Kyum Kim
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Clin Exp Pediatr. 1998;41(12):1650-1659. Published online December 15, 1998
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Purpose : This study was performed to observe the utilization of ultrasonography in locating the position of UAC and to compare the position with anatomical landmarks seen on radiography.
Methods : Optimal position is when the catheter tip is located between T6-T10 or L3-L5 by anteroposterior radiography(AP-R) and above the diaphragm by cross-table lateral radiography(CTL-R). Ultrasonographic studies used a Hewlett Packard... |
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- The Effect of Steroid Therapy on Growth and Bone Density in Children with Nephrotic Syndrome
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Seong Hoi Jeon, Ae Yeon Lim, Young Kook Kim, Hae Won Cheon, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee, Soon Kyum Kim
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Clin Exp Pediatr. 1998;41(10):1396-1402. Published online October 15, 1998
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Purpose : Long-term steroid therapy for various glomerular disorders in children has been known to decrease serum Vit D3 level and develop osteomalacia. The aim of this study was to observe the effect of long-term steroid therapy on growth and bone density in children with nephrotic syndrome.
Methods : Bone density of 17 steroid-treated nephrotic syndrome was compared with that of... |
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- Visual Evoked Potentials in Healthy Preterm Infants
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Young Kook Kim, Young Hwan Kim, Young Sook Hong
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Clin Exp Pediatr. 1997;40(9):1219-1226. Published online September 15, 1997
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Purpose : The visual evoked potentials(VEPs) offer a window both on visual system
function and on cerebral or neurologic function. The study was performed to evaluate
the maturation of VEP in preterm infants and to present a guide to detect high risk
neonates who can develop neurodevelopmental abnormalities.
Methods : The VEPs were recorded in response to binocular stimulus with
light-emitting diode goggles. VEP recordings... |
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- Somatosensory Evoked Potential of Median Nerve in Preterm Infants
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Young Hwan Kim, Kee Hwan Yoo, Young Sook Hong
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Clin Exp Pediatr. 1997;40(6):801-808. Published online June 15, 1997
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Purpose : The purpose of this study was to standardize the somatosensory evoked
potential(SEP) latency and amplitude of healthy preterm infants according to the postconceptional
age.
Methods : The median nerve SEPs were recorded in 30 healthy preterm infants who
were followed up until 6 months and were neurodevelopmentally normal.
Results : The mean peak latency and interpeak amplitude were following :
P0=20.89±6.09(msec), N1=26.32±5.18, P1=31.16±6.59, N2=36.52±7.22... |
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- Doppler Analysis of Postprandial Intestinal Blood Flow in Healthy Preterm Infants
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Yu In Park, Young Kook Kim, Young Sook Hong
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Clin Exp Pediatr. 1996;39(6):780-787. Published online June 15, 1996
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Purpose : The newborn period is a time of rapid physiological change in the gastrointestinal tract, when adaptation from a state of parenteral nutrition to the demands of enteral feeding take place. little is known about the intestinal vascular responses that accompany intestinal adaptive changes, although there is much speculation about the relationship between entreral feeding, alterations in gut perfusion,... |
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- Doppler Analysis of Renal Blood Flow in Normal Children
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Hyun Joo Kwak, Jae Yong Kim, Kee Hwan Yoo, Young Sook Hong, Joo Won Lee
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Clin Exp Pediatr. 1995;38(3):328-338. Published online March 15, 1995
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Purpose : Recent development in ultrasonic Doppler instrumentation have allowed the direct noninvasive assessment of human renal artery blood flow. The authors conducted this study to assess noninvasive characterization of normal renal artery blood flow variables hopping to establish standards in normal children.
Methods : A total 97 normal Subjects(below the age 3 years) were examinated using by 2-D and... |
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- A Study on Evolution of Lipoportein(a) in Newborns
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Keun Haeng Cho, Young Sook Hong, Soo Won Lee, Soon Kyum Kim, Young Chang Tockgo, Han Kyeom Kim
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Clin Exp Pediatr. 1994;37(8):1078-1091. Published online August 15, 1994
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Lipoprotein(a) [Lp(a)] is considered an additional, independent and largely genetically determined risk factor for the development of premature coronary heart disease.
Furthermore abnormal plasma lipoprotein patterns have been associated with increased risk for developing coronary heart disease. Among these lipoproteins, an increased concentration of serum Apo B and decreased level of Apo A are considered as major risk factors, together... |
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- Case Report
- A Case of Acute Tubular Necrosis Induced by paraquat (Gramoxon®) Intoxication
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Young Guk Kim, Dong Gun Park, Kee Hwan You, Keun Haeng Cho, Young Sook Hong, Soon Kyum Kim
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Clin Exp Pediatr. 1994;37(8):1143-1148. Published online August 15, 1994
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Paraquat (1, 1'-dimethy1-4, 4'dipyridium chlorde: Gramoxon¢c) was first discovered in England in 1955. It has been widely distributed for use in Korea since 1970 as a pesticide and also often the cause of accidental intoxications. The authors would like to report the following case of paraquat intoxication in a 13 year old female child admitted via emergency room with complaints... |
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- A Case of Xanthogranulonatous Pyelinephritis with Idiopathic Hypercalciruia in a Child
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Young Jun Kim, Hyun Joo Kwak, Keun Haeng Cho, Kee Hwan Yoo, Young Sook Hong, Soon Kyum Kim
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Clin Exp Pediatr. 1994;37(12):1778-1783. Published online December 15, 1994
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Xanthogranulomatous pyelonephritis in childhood is a rare chronic pyelonephritis often assodiated with calculi of urinary tract obstruction, with a clinical presentation of renal mass. A 3-year old boy was admitted to Korea University Hospital complaining of intermittent fever and palpable mass at right upper quadrant of the abdomen. The CBC revealed increased ESR and the finding of iron deficientcy anemia.... |
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- Original Article
- Clinical Investigation of Chlamydia Pneumonia in Infants.
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Jong Hoon Park, Se Geon Park, Kwang Chul Lee, Young Sook Hong, Young Chang vTockgo
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Clin Exp Pediatr. 1990;33(8):1065-1073. Published online August 31, 1990
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We performed chlamydia antigen test by enzyme immunoassay in 322 infants who were admitted
because of pneumonia. Clinical investigation and statistical analysis were done between chlamydia
antigen positive group and negative group.
The results obtain were as follows
1) Chlamydia antigen positive were resulted in 42 cases (13.04%) among 322 cases.
2) The mean age of Chlamydia positive and negative group were 14.2±6.2 weeks and 11.5±5.
7weeks respectively.
3) Afebrile... |
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- A clinicostatistical Study of Congenital Intestinal Obstruction.
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Min Young Lee, Young Sook Hong, Se Jin Kang, Soon Kyum Kim, Pyung Hwa Choe
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Clin Exp Pediatr. 1990;33(4):456-462. Published online April 30, 1990
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A clinicostatistical assessment of the 134 patients with congenital intestinal obstruction who were admitted
to the department of pediatrics and pediatric surgery. Korea university medical center from Feb. 1979 to June.
1988 was performed.
The results were as follows.
1) Congenital hypertrophic pyloric stenosis (43 cases) was the' most common congenital intestinal obstruc-
tion, and congenital megacolon (24 cases), imperforate anus (23 cases), omphalocele (11 cases),... |
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- A case of Evans Syndrome Associated with A-V Malformation.
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Keun Haeng Cho, Min Young Lee, Kwang Chul Lee, Young Sook Hong, Soon Kyum Kim
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Clin Exp Pediatr. 1989;32(6):839-844. Published online June 30, 1989
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In 1951, Evans and associates first described a group of patients with primary thrombocytopenic
purpura for a diagnosis of Evans syndrome, The criteria for a diagnosis of Evans syndrome were(l)
hemolytic anemia with a positive direct coombs’ test and thrombocytopenia occuring either simultaneously or in succession and(2) the absence of any known underlying etiology. We experienced a
case of Evans syndrome associated with... |
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- Congenital Esophageal Atresia Associated with Tracheal Bronchus and Imperforate Anus.
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Si Houn Hahn, Keun Haeng Cho, Young Sook Hong, Soon Kyum Kim
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Clin Exp Pediatr. 1989;32(4):550-555. Published online April 30, 1989
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Esophageal atresia occurs once in 3000-4500 live births. These anomalies are thought to arise from
defective differentiation of the primitive foregut into trachea and esophagus. defective growth of
entodermal cells leading to atresia and an incomplete fusion of the lateral walls of the foregut to form
a tracheoesophageal fistula.
A full-term male baby was admitted to Guro Hospital with chief complaints of respiratory
difficulty, chocking,... |
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- A Case of Cleidocranial Dysostosis with Leukemia.
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Baik Lin eun, Si Hun Han, Young Sook Hong, Soon Kyum Kim
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Clin Exp Pediatr. 1988;31(7):930-934. Published online July 31, 1988
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Cleidocranial dysostosis is a rare, inherited abnormality which affects the development of mem-
bransous and cartilaginous bone.
Authors report a case of cleidocranial dysostosis with leukemia in a 10 year old boy.
The review of the literature was made briefly. |
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- A Case of Juvenile Chronic Myelogenous Leukemia Associated with Juvenile Xanthogranuloma.
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Eun Yong Lee, Jin Tae Kim, Young Sook Hong, Soon Kyun Kim, Hyun Keum Lee
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Clin Exp Pediatr. 1987;30(11):1299-1304. Published online November 30, 1987
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We experienced a case of juvenile chronic myelogenous leukemia associated with juvenile xanthogranuloma
and neurofibromatosis.
This 1-year 6-month-old male patient had multipe cafg-au-lait spots, numerous nontender, yellowish,
dome-shaped papules and nodules, hepatosplenomegaly, and pneumonia.
Hematologic & bone marrow examinations, chromosomal study, and skin biopsy were performed for diagnosis.
A brief review of the related literatures was added.
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- Case Report
- Congenital Hiatal Hernia Associated with Anemia.
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Young Sook Hong, Young Mo Sohn, Pyung Kil Kim
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Clin Exp Pediatr. 1982;25(5):523-527. Published online May 31, 1982
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Surgically corrected congenital hiatal hernia associated with anemia has been presented. A 1 year old boy has been complained of severe pallor and fever on admission. Reentgenologic examination revealed thoracic stomach and then the hernia was repaired by transabdominal approach. It was found to be a paraesophageal type hiatal hernia. Pathogenesis and complications of congenital histal hernia were discussed and... |
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- Original Article
- A Clinical Study on Acute Appendicitis in Children.
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Young Sook Hong, Jae Sook Kim, Nam Ji Cho, Ki Ung Hong
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Clin Exp Pediatr. 1982;25(4):373-378. Published online April 30, 1982
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A Clinic study was made on 140 cases of acute appendicitis in children under the age of 15 which were treated at National Seoul Hospital during the past 10 years from Jan. 1971 to dec. 1980. The following results were obtained. 1) The disease is relatively uncommon under the age of 6, and showed a progressive increase from 6 to... |
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- Case Report
- A Case of Anencephalus in Single-Ovum Twin.
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Young Sook Hong, Young Hee Yoo, Hea Sook Kwon, Nam Ji Cho
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Clin Exp Pediatr. 1981;24(2):184-186. Published online February 15, 1981
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A case of anencephalus in single-ovum twin was observed at National Seoul Hospital and Is presented. Diagnosis of anencephalic fetus was made by abdominal Xray of mother. And a brief review on anencephalus is presented.
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- A Case of Congenital Partial Anonychia.
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Young Hee Yoo, Moon Ki Cho, Young Sook Hong, Hae Sook Kwon, Nam Ji Cho
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Clin Exp Pediatr. 1980;23(9):766-770. Published online September 15, 1980
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The congenital partial anonychia is known to be very rare developmental anomalies of the nail. Recently, we experienced a case of congenital partial anonychiain male newborn infant due to autosomal dominance. In this condition there complete absence of nails on the both thumb, index, middle fingers and toes were affected in a similar way to the fingers. But there were... |
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- Original Article
- Statistical Observation of the time of first stool and first void in 800 newborns.
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Moon Ki Cho, Young Hee Yoo, Young Sook Hong, Hae Sook Kwan, Nam Ji Cho
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Clin Exp Pediatr. 1980;23(8):637-645. Published online August 15, 1980
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The statistical observation of the time of passage of the first stool and first void was performed on 800 cases of newborns, were carried at the newborn nursery and premature baby room, National Seoul Hospital, during the past two years from Jan, 1977 to Dec, 1978. The population study was performed on sex, gestational age, Apgar score, mode of delivery,... |
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